LUNA: Efficient and Topology-Agnostic Foundation Model for EEG Signal Analysis
Berkay Döner,
Thorir Mar Ingolfsson,
Luca Benini,
Yawei Li
December 2025
Abstract
Electroencephalography (EEG) datasets use heterogeneous electrode layouts, which hampers the generalization of large-scale models. LUNA (Latent Unified Network Architecture) is a self-supervised foundation model that compresses multi-channel EEG into a topology-agnostic latent space, allowing patch-wise linear and cross-attention operations that decouple computation from electrode count. Trained on more than 21,000 hours of TUEG and Siena EEG using a masked reconstruction objective, LUNA transfers to tasks such as abnormality detection, artifact rejection, slowing classification, and emotion recognition, achieving state-of-the-art AUROC on TUAR and TUSL while reducing FLOPs by 300× and GPU memory consumption by 10×.
Key Highlights
- Compresses multi-channel EEG into a topology-agnostic latent space that decouples computation from electrode count.
- Pre-trained on more than 21,000 hours of EEG data and transfers to abnormality detection, artifact rejection, slowing classification, and emotion recognition.
- Achieves 0.921 AUROC on TUAR while reducing FLOPs by 300× and GPU memory requirements by 10×.
Resources
Postdoctoral Researcher
I develop efficient machine learning systems for biomedical wearables that operate under extreme resource constraints. My work bridges foundation models, neural architecture design, and edge deployment to enable real-time biosignal analysis on microwatt-scale devices.